import re
re.sub('[^A-Za-z0-9]+', '', mystring)
>>> string = "Special $#! characters spaces 888323"
>>> ''.join(e for e in string if e.isalnum())
'Specialcharactersspaces888323'
import re
my_list= ["on@3", "two#", "thre%e"]
print [re.sub('[^a-zA-Z0-9]+', '', _) for _ in my_list]